FreeCAD is an Open Source CAx RAD based on Open Cascade, Qt and Python. It features some key concepts like Macro recording, Workbenches, ability to run as a server and dynamically loadable Application extensions and its designed to be platform independent.
Fandango is planned to be a full featured CAD program and has C++ core extensible by scripts. Currently the memory core for entity management is ready, scripting works wonderfully thanks to the ease of embedding and extending of Python. A KDE+XML user interface is now in place, controlling the keyboard and mouse.
Vintech RCAM is a CAD/CAM system for true shape nesting and NC programming of laser, plasma, oxy-fuel and water-jet cutting machines. Vintech RCAM is platform independent and now it runs under Windows XP, Windows 7 and Linux. The main programing language of the system is Python, which defines the advanced methodology and the dynamic system development.